ANGPT2 (Human) Recombinant Protein
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Specification
Product Description
Human ANGPT2 (O15123, 19 a.a. - 496 a.a.) partial-length recombinant protein with His-tag at C-terminal expressed in CHO cell.
Amount
> 90% by SDS-PAGE
Sequence
YNNFRKSMDSIGKKQYQVQHGSCSYTFLLPEMDNCRSSSSPYVSNAVQRDAPLEYDDSVQRLQVLENIMENNTQWLMKLENYIQDNMKKEMVEIQQNAVQNQTAVMIEIGTNLLNQTAEQTRKLTDVEAQVLNQTTRLELQLLEHSLSTNKLEKQILDQTSEINKLQDKNSFLEKKVLAMEDKHIIQLQSIKEEKDQLQVLVSKQNSIIEELEKKIVTATVNNSVLQKQQHDLMETVNNLLTMMSTSNSAKDPTVAKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQRREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFYLSSEELNYRIHLKGLTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWFDACGPSNLNGMYYPQRQNTNKFNGIKWYYWKGSGYSLKATTMMIRPADFHHHHHH
Host
Human
Theoretical MW (kDa)
55.7
Form
Liquid
Preparation Method
CHO cell expression system
Storage Buffer
Phosphate buffered saline (pH7.4) and 10% glycerol.
Storage Instruction
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles. -
Applications
SDS-PAGE
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Gene Info — ANGPT2
Entrez GeneID
285Protein Accession#
O15123Gene Name
ANGPT2
Gene Alias
AGPT2, ANG2
Gene Description
angiopoietin 2
Omim ID
601922Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Tie2-ligand|angiopoietin-2|angiopoietin-2B|angiopoietin-2a
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Interactome
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Disease
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