IL17A (Human) Recombinant Protein

Catalog # P8358

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Price

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Quantity

Size:2 x 10 ug
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Human IL17A (Q16552, 24 a.a. - 155 a.a.) partial recombinant protein with His tag at C-terminus expressed in Sf9 cells.

    Sequence

    GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVAHHHHHH

    Host

    insect

    Theoretical MW (kDa)

    15.9

    Form

    Liquid

    Preparation Method

    Sf9 cell expression system

    Purity

    > 90% by SDS-PAGE

    Recommend Usage

    Biological Activity
    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 20mM PBS pH 7.4 (0.1mM PMSF, 1mM EDTA, 20% glycerol)

    Storage Instruction

    Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.

  • Applications

    SDS-PAGE

  • Gene Info — IL17A

    Entrez GeneID

    3605

    Protein Accession#

    Q16552

    Gene Name

    IL17A

    Gene Alias

    CTLA8, IL-17, IL-17A, IL17

    Gene Description

    interleukin 17A

    Omim ID

    603149

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq

    Other Designations

    OTTHUMP00000016597|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|cytotoxic T-lymphocyte-associated serine esterase 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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