IL7 (Human) Recombinant Protein
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Specification
Product Description
Human IL7 (P13232) partial recombinant protein expressed in HEK293 cells.
Host
Mammals
Theoretical MW (kDa)
19-30
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% by SDS-PAGE
Activity
The activity was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells and is typically 0.3 ng/mL corresponding to a specific activity of 3333334 units/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% endotoxin-free recombinant HAS)
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — IL7
Entrez GeneID
3574Protein Accession#
P13232Gene Name
IL7
Gene Alias
IL-7
Gene Description
interleukin 7
Omim ID
146660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq
Other Designations
IL7 nirs variant 6
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Interactome
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