IGFBP1 (Human) Recombinant Protein
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Specification
Product Description
Human IGFBP1 (P08833, 26 a.a. - 259 a.a.) partial recombinant protein expressed in Mouse myeloma cell line.
Sequence
APWQCAPCSAEKLALCPPVSASCSEVTRSAGCGCCPMCALPLGAACGVATARCARGLSCRALPGEQQPLHALTRGQGACVQESDASAPHAAEAGSPESPESTEITEEELLDNFHLMAPSEEDHSILWDAISTYDGSKALHVTNIKKWKEPCRIELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEIRGDPNCQIYFNVQN
Host
Mouse
Theoretical MW (kDa)
25
Form
Lyophilized
Preparation Method
Mouse myeloma cell line,NS0 expression system
Purity
> 95% by SDS-PAGE
Activity
The ED50 as determined bythe inhibition of rHuIGF-I-induced proliferation of human MCF-7 cells is < 4 ug/mL.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IGFBP1
Entrez GeneID
3484Protein Accession#
P08833Gene Name
IGFBP1
Gene Alias
AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
Gene Description
insulin-like growth factor binding protein 1
Omim ID
146730Gene Ontology
HyperlinkGene Summary
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq
Other Designations
IGF-binding protein 1|alpha-pregnancy-associated endometrial globulin|amniotic fluid binding protein|binding protein-25|binding protein-26|binding protein-28|growth hormone independent-binding protein|placental protein 12
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Interactome
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Disease
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