TIGIT (Human) Recombinant Protein
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Result of bioactivity analysis
Result of bioactivity analysis
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Specification
Product Description
Human TIGIT (Q495A1, 22 a.a. - 141 a.a.) partial recombinant protein with His tag at C-terminus expressed in HEK293+J15 cells.
Sequence
MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIP
Host
Mammals
Theoretical MW (kDa)
16
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 90% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by gel clotting method)
Activity
This proten can bind with CHO-K1/aAPC/CD155 Clone by FACS analysis.
Storage Buffer
Lyophilized from sterile distilled Water up to 100 ug/mL
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — TIGIT
Entrez GeneID
201633Protein Accession#
Q495A1Gene Name
TIGIT
Gene Alias
DKFZp667A205, FLJ39873, VSIG9, VSTM3
Gene Description
T cell immunoreceptor with Ig and ITIM domains
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses
Other Designations
V-set and immunoglobulin domain containing 9|V-set and transmembrane domain containing 3
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