PDGFD (Human) Recombinant Protein
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Specification
Product Description
Human PDGFD (Q9GZP0, 250 a.a. - 370 a.a.) partial recombinant protein expressed in CHO cells.
Sequence
SYHDRKSKVDLDRLNDDAKRYSCTPRNYSVNIREELKLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCICSSRPPR
Host
Mammals
Theoretical MW (kDa)
19~ 21
Form
Lyophilized
Preparation Method
Mammalian cell (CHO) expression system
Purity
> 95% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/ ug of protein (gel clotting method)
Activity
ED50 < 5.0 ug/mL, measured in a cell proliferation assay using 3T3 cells.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 ug/mL.
Storage Instruction
Store at 4°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — PDGFD
Entrez GeneID
80310Protein Accession#
Q9GZP0Gene Name
PDGFD
Gene Alias
IEGF, MGC26867, MSTP036, SCDGF-B, SCDGFB
Gene Description
platelet derived growth factor D
Omim ID
609673Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq
Other Designations
iris-expressed growth factor|spinal cord derived growth factor B|spinal cord-derived growth factor-B
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Interactome
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Disease
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