IFNGR2 (Human) Recombinant Protein
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Specification
Product Description
Human IFNGR2 (P38484, 28 a.a. - 247 a.a ) partial recombinant protein expressed in CHO cells.
Sequence
SQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRPVVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYWEKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMADASTELQQ
Host
Mammals
Theoretical MW (kDa)
38 - 40
Form
Lyophilized
Preparation Method
Mammalian cell (CHO) expression system
Purity
> 95% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/ug of protein by gel clotting method
Activity
ED50 < 0.1 ug/mL, measured in a cell cytotoxicity assay using HT-29 (HTB-38) cells in the presence of 1.0 ng/mL human IFN-gamma.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O up to 100 ug/mL.
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IFNGR2
Entrez GeneID
3460Protein Accession#
P38484Gene Name
IFNGR2
Gene Alias
AF-1, IFGR2, IFNGT1
Gene Description
interferon gamma receptor 2 (interferon gamma transducer 1)
Gene Ontology
HyperlinkGene Summary
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq
Other Designations
interferon gamma receptor 2|interferon gamma receptor accessory factor-1|interferon gamma receptor beta chain
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