PDGFC (Human) Recombinant Protein
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Result of activity analysis
Result of activity analysis
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Specification
Product Description
Human PDGFC (Q9NRA1, 235 a.a. - 345 a.a ) partial recombinant protein expressed in HEK293 cells.
Sequence
VVDLNLLTEEVRLYSCTPRNFSVSIREELKRTDTIFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRPKTGVRGLHKSLTDVALEHHEECDCVCRGSTGG
Host
Human
Theoretical MW (kDa)
15 - 19
Form
Lyophilized
Preparation Method
Mammalian cell (HEK 293) expression system
Purity
> 95% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/ug of protein by gel clotting method
Activity
ED50 < 1.0 ng/mL, measured in a cell proliferation assay using 3T3 cells.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O up to 100 ug/mL.
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — PDGFC
Entrez GeneID
56034Protein Accession#
Q9NRA1Gene Name
PDGFC
Gene Alias
FALLOTEIN, SCDGF
Gene Description
platelet derived growth factor C
Omim ID
608452Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. [provided by RefSeq
Other Designations
platelet-derived growth factor C|secretory growth factor-like protein|spinal cord-derived growth factor
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Interactome
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Pathway
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Disease
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