IFNL1 (Human) Recombinant Protein
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Specification
Product Description
Human IFNL1 (Q8IU54, 20 a.a. - 200 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
GPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGNLCLRTSTHPEST
Host
Escherichia coli
Theoretical MW (kDa)
19.8
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The ED50 was determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is < 5.0 ng/ml, corresponding to a specific activity of > 2.0 × 105 IU/mg.
Storage Buffer
Lyophilized from sterile distilled Water up to 0.1 - 1.0 mg/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL29
Entrez GeneID
282618Protein Accession#
Q8IU54Gene Name
IL29
Gene Alias
IFNL1, IL-29
Gene Description
interleukin 29 (interferon, lambda 1)
Omim ID
607403Gene Ontology
HyperlinkGene Summary
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq
Other Designations
interferon, lambda 1|interleukin 29
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