IL17F (Human) Recombinant Protein
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Specification
Product Description
Human IL17F (Q96PD4, 31 a.a. - 163 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
RKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQ
Host
Escherichia coli
Theoretical MW (kDa)
30.1
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The ED50 was determined by inducing IL-6 secretion of murine NIH/3T3 cell is < 20.0 ng/ml, corresponding to a specific activity of > 5.0 x 104 IU/mg.
Storage Buffer
Lyophilized from 4 mM HCl up to 100 ug/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL17F
Entrez GeneID
112744Protein Accession#
Q96PD4Gene Name
IL17F
Gene Alias
IL-17F, ML-1, ML1
Gene Description
interleukin 17F
Omim ID
606496Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq
Other Designations
cytokine ML-1
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Interactome
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Disease
- Arthritis
- Asthma
- Behcet Syndrome
- Cardiovascular Diseases
- Colitis
- Crohn Disease
- Dermatitis
- Diabetes Mellitus
- Dyspepsia
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