IL11 (Human) Recombinant Protein
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Specification
Product Description
Human IL11 (P202809-1, 22 a.a. - 199 a.a.) partial recombinant protein expressed in CHO cell.
Sequence
PGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSL
Host
Mammals
Theoretical MW (kDa)
23
Form
Lyophilized
Preparation Method
Mammalian cell (CHO) expression system
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 0.2 EU per 1 ug of protein (determined by gel clotting method).
Activity
ED50 < 5.0 ng/ml, measured in a proliferation assay using T11 cells.
Storage Buffer
Lyophilized from PBS up to 100 ug/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — IL11
Entrez GeneID
3589Protein Accession#
P20809-1Gene Name
IL11
Gene Alias
AGIF, IL-11
Gene Description
interleukin 11
Omim ID
147681Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. [provided by RefSeq
Other Designations
adipogenesis inhibitory factor|oprelvekin
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