NRN1 (Human) Recombinant Protein
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Specification
Product Description
Human NRN1 (Q9NPD7) recombinant protein expressed in E. Coli.
Sequence
AGKCDAVFKGFSDCLLKLGDSMANYPQGLDDKTNIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLFELCGSGN
Host
Escherichia coli
Theoretical MW (kDa)
10
Form
Lyophilized
Purity
> 95%
Endotoxin Level
<= 1 EUs/ug (LAL gel clot method)
Activity
Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20-30 ng/mL.
Storage Buffer
Lyophilized from PBS, pH 7.2.
Storage Instruction
Stored at -20°C to-80°C.
After reconstitution with sterile water not less than 0.1 mg/mL, store at -20°C to -80°C for 6 months, store at 4°C for 1 month.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Functional Study
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Gene Info — NRN1
Entrez GeneID
51299Protein Accession#
Q9NPD7Gene Name
NRN1
Gene Alias
MGC44811, NRN, dJ380B8.2
Gene Description
neuritin 1
Omim ID
607409Gene Ontology
HyperlinkGene Summary
This gene is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000015989|neuritin
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