MAPKAPK2 (Human) Recombinant Protein
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Specification
Product Description
Human MAPKAPK2 (NM_004759, 1 a.a.- 370 a.a.) full-length recombinant protein expressed in Sf9 cells.
Host
insect
Theoretical MW (kDa)
42.329
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purification
Immobilized metal affinity chromatography
Concentration
0.340 ug/uL
Activity
101 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Hepes, 100 mM NaCl, pH 7.5. (5 mM DTT, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — MAPKAPK2
Entrez GeneID
9261Protein Accession#
NM_004759Gene Name
MAPKAPK2
Gene Alias
MK2
Gene Description
mitogen-activated protein kinase-activated protein kinase 2
Omim ID
602006Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034531|OTTHUMP00000034532
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