HTRA2 (Human) Recombinant Protein

Catalog # P3519

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Size:100 ug
Price: USD $ 236.00
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  • +1-909-264-1399
    +1-909-992-0619
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  • +1-909-992-3401
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  • Specification

    Product Description

    Human HTRA2 (NP_037379, 134 a.a. - 458 a.a.) partial recombinant protein with His tag expressed in Escherichia coli.

    Sequence

    MAVPSPPPASPPSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNAGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTEGSHHHHHH

    Host

    Escherichia coli

    Theoretical MW (kDa)

    36

    Form

    Liquid

    Preparation Method

    Escherichia coli expression system

    Purification

    Conventional Chromatography

    Concentration

    0.5 mg/mL

    Purity

    > 95% by SDS-PAGE

    Quality Control Testing

    Loading 3 ug protein in 15% SDS-PAGE

    Storage Buffer

    In 20 mM Tris-HCl buffer, 50 mM NaCl, pH 8.0 (1 mM DTT, 20% glycerol).

    Storage Instruction

    Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
    Aliquot to avoid repeated freezing and thawing.

  • Applications

    SDS-PAGE

  • Gene Info — HTRA2

    Entrez GeneID

    27429

    Protein Accession#

    NP_037379

    Gene Name

    HTRA2

    Gene Alias

    OMI, PARK13, PRSS25

    Gene Description

    HtrA serine peptidase 2

    Omim ID

    606441 610297

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq

    Other Designations

    HtrA-like serine protease|Omi stress-regulated endoprotease|high temperature requirement protein A2|protease, serine, 25

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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