GNRHR monoclonal antibody, clone AT2.G7
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of GNRHR monoclonal antibody, clone AT2.G7 (Cat # MAB8771) in GNRHR protein.
Lane 1 and 2 : Tissue extracts from normal ovaries.
Lane 3 to 9 : Tissue extracts from different stage of ovarian cancers.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of GNRHR.
Immunogen
A mixture of peptides from different regions of human GNRHR.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Concentration
1 ug/uL
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of GNRHR monoclonal antibody, clone AT2.G7 (Cat # MAB8771) in GNRHR protein.
Lane 1 and 2 : Tissue extracts from normal ovaries.
Lane 3 to 9 : Tissue extracts from different stage of ovarian cancers.Immunohistochemistry
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Gene Info — GNRHR
Entrez GeneID
2798Gene Name
GNRHR
Gene Alias
GNRHR1, GRHR, LHRHR, LRHR
Gene Description
gonadotropin-releasing hormone receptor
Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq
Other Designations
gonadotropin-releasing hormone (type 1) receptor 1|leutinizing hormone releasing horomone receptor|leutinizing-releasing hormone receptor|luliberin receptor|type I GnRH receptor
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Interactome
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Pathway
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Disease
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