ITGA4 monoclonal antibody, clone BU49
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against native ITGA4.
Immunogen
Native purified ITGA4 from human peripheral myeloma cells.
Host
Mouse
Reactivity
Human
Specificity
Antibody BU49 blocks VLA-4 binding to VCAM-1.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
-
Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
-
Gene Info — ITGA4
Entrez GeneID
3676Gene Name
ITGA4
Gene Alias
CD49D, IA4, MGC90518
Gene Description
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
Omim ID
192975Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. [provided by RefSeq
Other Designations
269C wild type|antigen CD49D, alpha-4 subunit of VLA-4 receptor|integrin alpha 4|integrin alpha-4 subunit|very late activation protein 4 receptor, alpha 4 subunit
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Role of the VLA-4 molecule in T cell costimulation. Identification of the tyrosine phosphorylation pattern induced by the ligation of VLA-4.
Sato T, Tachibana K, Nojima Y, D'Avirro N, Morimoto C.
Journal of Immunology 1995 Sep; 155(6):2938.
Application:IA, Human, Jurkat cells.
-
Role of the VLA-4 molecule in T cell costimulation. Identification of the tyrosine phosphorylation pattern induced by the ligation of VLA-4.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com