FUT4 monoclonal antibody, clone AHN1.1
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Specification
Product Description
Mouse monoclonal antibody raised against native FUT4.
Immunogen
Native purified FUT4 from human neutrophils.
Host
Mouse
Reactivity
Human
Specificity
Antibody AHN1.1 activates normal monocytes and inhibits neutrophil chemotaxis.
Form
Liquid
Isotype
IgM
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — FUT4
Entrez GeneID
2526Gene Name
FUT4
Gene Alias
CD15, ELFT, FCT3A, FUC-TIV, FUTIV
Gene Description
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Omim ID
104230Gene Ontology
HyperlinkGene Summary
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq
Other Designations
ELAM ligand fucosyltransferase|fucosyltransferase 4|fucosyltransferase IV|galactoside 3-L-fucosyltransferase
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Interactome
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Pathway
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Publication Reference
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The role of CD15-(Le(X))-related carbohydrates in neutrophil adhesion.
Kerr MA, Stocks SC.
The Histochemical Journal 1992 Nov; 24(11):811.
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A human granulocyte-specific antigen characterized by use of monoclonal antibodies.
Skubitz KM, Zhen Y, August JT.
Blood 1983 Jan; 61(1):19.
Application：IF, IP, Human, Human neutrophils.
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The role of CD15-(Le(X))-related carbohydrates in neutrophil adhesion.
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