Hcn2 monoclonal antibody, clone S71
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant Hcn2.
Immunogen
Recombinant fusion protein corresponding to amino acids 761-863 of rat Hcn2.
Host
Mouse
Reactivity
Human, Mouse, Rat
Specificity
Detects ~95KDa. No cross-reactivity against HCN1.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1-10 ug/mL)
Immunohistochemistry (0.1-1.0 ug/mL)
Immunocytochemistry (0.1-1.0 ug/mL)
Immunofluorescence (1.0-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunofluorescence
Immunofluorescence staining in human hippocampus with Hcn2 monoclonal antibody, clone S71 (Cat # MAB6652).Immunoprecipitation
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Gene Info — Hcn2
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Publication Reference
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Congenital long QT syndrome.
Crotti L, Celano G, Dagradi F, Schwartz PJ.
Orphanet Journal of Rare Diseases 2008 Jul; 3:18.
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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT.
Cell 2004 Oct; 119(1):19.
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Congenital long QT syndrome.
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