DDX39 monoclonal antibody, clone 2E4
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More Files
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Immunohistochemistry
Immunohistochemical satining of rat testis tissue with DDX39 monoclonal antibody, clone 2E4 (Cat # MAB6576).
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of DDX39.
Immunogen
A synthetic peptide corresponding to N-terminus of human DDX39.
Host
Mouse
Reactivity
Human, Rat
Form
Liquid
Recommend Usage
ELISA (1 ug/mL)
Immunohistochemistry (3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2% Block Ace)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunohistochemical satining of rat testis tissue with DDX39 monoclonal antibody, clone 2E4 (Cat # MAB6576).Enzyme-linked Immunoabsorbent Assay
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Gene Info — DDX39
Entrez GeneID
10212Gene Name
DDX39
Gene Alias
BAT1, BAT1L, DDXL, MGC18203, MGC8417, URH49
Gene Description
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. [provided by RefSeq
Other Designations
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 transcript|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39|UAP56-related helicase, 49 kDa|nuclear RNA helicase, DECD variant of DEAD box family
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Interactome
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Publication Reference
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The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection.
Iulia Tapescu, Frances Taschuk, Swechha M Pokharel, Oleksandr Zginnyk, Max Ferretti, Peter F Bailer, Kanupryia Whig, Emily A Madden, Mark T Heise, David C Schultz, Sara Cherry.
Molecular Cell 2023 Nov; 83(22):4174.
Application：IF, IP, WB, Human, HEK293T, U20S cells.
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Intracellular characterization of DDX39, a novel growth-associated RNA helicase.
Sugiura T, Sakurai K, Nagano Y.
Experimental Cell Research 2007 Feb; 313(4):782.
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Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.
Pryor A, Tung L, Yang Z, Kapadia F, Chang TH, Johnson LF.
Nucleic Acids Research 2004 Mar; 32(6):1857.
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K
Nature Genetics 2003 Dec; 36(1):40.
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The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection.
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