Kit monoclonal antibody, clone 2B8
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More Files
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Flow Cytometry
BALB/c bone marrow cells were double-stained with Kit monoclonal antibody-PE and rat anti-mouse Ly-6G-FITC, following which total cells were analyzed by flow cytometry.
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Specification
Product Description
Rat monoclonal antibody raised against native Kit.
Immunogen
Native purified Kit form murine bone marrow mast cells.
Host
Rat
Reactivity
Mouse
Specificity
The monoclonal antibody NIMR-4 reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.
Form
Liquid
Isotype
IgG2b
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Flow Cytometry
BALB/c bone marrow cells were double-stained with Kit monoclonal antibody-PE and rat anti-mouse Ly-6G-FITC, following which total cells were analyzed by flow cytometry. -
Gene Info — Kit
Entrez GeneID
16590Gene Name
Kit
Gene Alias
Bs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT
Gene Description
kit oncogene
Gene Ontology
HyperlinkOther Designations
Dominant white spotting|Steel Factor Receptor|belly-spot|c-kit|c-kit proto-oncogene protein|dominant spotting|spotted sterile male
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Publication Reference
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Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen.
Broudy VC, Lin NL, Priestley GV, Nocka K, Wolf NS.
Blood 1996 Jul; 88(1):75.
Application：Blocking, Func, Mouse, Femurs, Reticulocytes, Spleens.
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Distinct stages of melanocyte differentiation revealed by anlaysis of nonuniform pigmentation patterns.
Yoshida H, Kunisada T, Kusakabe M, Nishikawa S, Nishikawa SI.
Development 1996 Apr; 122(4):1207.
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Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M.
Sudo T, Nishikawa S, Ogawa M, Kataoka H, Ohno N, Izawa A, Hayashi S, Nishikawa S.
Oncogene 1995 Dec; 11(12):2469.
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Interaction of stem cell factor and its receptor c-kit mediates lodgment and acute expansion of hematopoietic cells in the murine spleen.
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