ITGA1 monoclonal antibody, clone TS2/7
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Specification
Product Description
Mouse monoclonal antibody raised against native ITGA1.
Immunogen
Native purified ITGA1 from human thymoma cell line HPB-ALL.
Host
Mouse
Reactivity
Human
Specificity
TS2/7 recognizes the human alpha 1 integrin sub-unit, which forms the VLA-1 heterodimer in association with the beta 1 integrin. VLA-1 is a receptor for collagen and laminin, and is expressed by chronically activated T cells, melanoma cells and smooth muscle cells.
Form
Liquid
Isotype
IgG1
Recommend Usage
Flow Cytometry (5 ul of the antibody (neat) to label 106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — ITGA1
Entrez GeneID
3672Gene Name
ITGA1
Gene Alias
CD49a, VLA1
Gene Description
integrin, alpha 1
Omim ID
192968Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq
Other Designations
laminin and collagen receptor|very late activation protein 1
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Interactome
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