NCAM1 monoclonal antibody, clone MEM-188 (PerCP)
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Specification
Product Description
Mouse monoclonal antibody raised against native NCAM1.
Immunogen
Native purified NCAM1 from KG-1 human acute myelogenous leukemia cell line.
Host
Mouse
Theoretical MW (kDa)
180
Reactivity
Human, Primates
Specificity
This antibody reacts with a 180 KDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that This antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
Form
Liquid
Conjugation
PerCP
Isotype
IgG2a
Recommend Usage
Flow Cytometry analysis of human blood cells using 10 ul reagent / 100 ul of whole blood or 106 cells in a suspension.
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.2% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — NCAM1
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Interactome
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Pathway
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Disease
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Publication Reference
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Down-regulation of the axonal polysialic acid-neural cell adhesion molecule expression coincides with the onset of myelination in the human fetal forebrain.
Jakovcevski I, Mo Z, Zecevic N.
Neuroscience 2007 Aug; 149(2):328.
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CD56 is a sensitive and diagnostically useful immunohistochemical marker of ovarian sex cord-stromal tumors.
McCluggage WG, McKenna M, McBride HA.
International Journal of Gynecological Pathology: Official Journal of the International Society of G 2007 Jul; 26(3):322.
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CD56 expression in ovarian granulosa cell tumors, and its diagnostic utility and pitfalls.
Ohishi Y, Kaku T, Oya M, Kobayashi H, Wake N, Tsuneyoshi M.
Gynecologic Oncology 2007 Jun; 107(1):30.
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Down-regulation of the axonal polysialic acid-neural cell adhesion molecule expression coincides with the onset of myelination in the human fetal forebrain.
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