SERPINF1/SERPINF2 monoclonal antibody, clone B3022M
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Specification
Product Description
Mouse monoclonal antibody raised against SERPINF1/SERPINF2.
Immunogen
Human SERPINF1/SERPINF2.
Host
Mouse
Reactivity
Human
Specificity
human Alpha 2 Antiplasmin.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (reduced and non-reduced) (1-5 ug/mL)
ELISA (1:50000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM NaCl, 1 mM EDTA, pH 6.6
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
Enzyme Immunoassay
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Gene Info — SERPINF1
Entrez GeneID
5176Gene Name
SERPINF1
Gene Alias
EPC-1, PEDF, PIG35
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Omim ID
172860Gene Ontology
HyperlinkGene Summary
The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.[supplied by OMIM
Other Designations
pigment epithelium-derived factor|proliferation-inducing protein 35|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
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Gene Info — SERPINF2
Entrez GeneID
5345Gene Name
SERPINF2
Gene Alias
A2AP, AAP, ALPHA-2-PI, API, PLI
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Omim ID
262850Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
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Interactome
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Pathway
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Disease
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