CPNE7 monoclonal antibody, clone CPNE7-01
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blotting analysis of CPNE7 using CPNE7 monoclonal antibody, clone CPNE7-01 (Cat # MAB3603) in nuclear cell lysate (1) and cytoplasmic fraction (2) of HeLa cell extracts.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CPNE7.
Immunogen
Recombinant GST fusion protein corresponding to C-terminus human CPNE7.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes C terminus of human CPNE7, a calcium-bindingcytoplasmic protein expressed mainly in brain.
Form
Liquid
Isotype
IgG
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blotting analysis of CPNE7 using CPNE7 monoclonal antibody, clone CPNE7-01 (Cat # MAB3603) in nuclear cell lysate (1) and cytoplasmic fraction (2) of HeLa cell extracts. -
Gene Info — CPNE7
Entrez GeneID
27132Gene Name
CPNE7
Gene Alias
MGC34192
Gene Description
copine VII
Omim ID
605689Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the copine family, which is composed of calcium-dependent membrane-binding proteins. The gene product contains two N-terminal C2 domains and one von Willebrand factor A domain. The encoded protein may be involved in membrane trafficking. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000175355|copine 7
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Interactome
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Publication Reference
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No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
Kniazeff J, Galvez T, Labesse G, Pin JP.
Journal of Neuroscience 2002 Sep; 22(17):7352.
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Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors.
Margeta-Mitrovic M, Jan YN, Jan LY.
PNAS 2001 Nov; 98(25):14649.
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Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.
Ng GY, Bertrand S, Sullivan R, Ethier N, Wang J, Yergey J, Belley M, Trimble L, Bateman K, Alder L, Smith A, McKernan R, Metters K, O'Neill GP, Lacaille JC, Hébert TE.
Molecular Pharmacology 2001 Jan; 59(1):144.
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No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
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