TNFSF13B monoclonal antibody, clone Buffy-2
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Staining of paraffin section of synovial tissue from a patient with Rheumatoid Arthritis. Arrows indicate vessels (20X) staining positive for TNFSF13B using TNFSF13B monoclonal antibody, clone Buffy-2 (Cat # MAB3371).
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Specification
Product Description
Rat monoclonal antibody raised against partial recombinant TNFSF13B.
Immunogen
Recombinant protein corresponding to amino acids 83-285 of human TNFSF13B.
Host
Rat
Reactivity
Human, Mouse
Specificity
Recognizes membrane-bound and soluble human and mouse (weak) BAFF.
Form
Liquid
Isotype
IgM
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Staining of paraffin section of synovial tissue from a patient with Rheumatoid Arthritis. Arrows indicate vessels (20X) staining positive for TNFSF13B using TNFSF13B monoclonal antibody, clone Buffy-2 (Cat # MAB3371).Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — TNFSF13B
Entrez GeneID
10673Gene Name
TNFSF13B
Gene Alias
BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4
Gene Description
tumor necrosis factor (ligand) superfamily, member 13b
Omim ID
603969Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq
Other Designations
ApoL related ligand TALL-1|B-cell activating factor|B-lymphocyte stimulator|OTTHUMP00000018691|TNF and ApoL-related leukocyte expressed ligand 1|TNF homolog that activates apoptosis|delta BAFF|dendritic cell-derived TNF-like molecule|tumor necrosis factor
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Interactome
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Pathway
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Disease
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