Fasl monoclonal antibody, clone A11
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Specification
Product Description
Rat monoclonal antibody raised against synthetic peptide of Fasl.
Immunogen
A synthetic peptide corresponding to amino acids 196-220 of mouse Fasl.
Host
Rat
Reactivity
Mouse
Specificity
Fas Ligand (FasL) is a type II membrane protein and a member of the tumor necrosis factor family. When interacting with the Fas receptor, the trimeric FasL induces apoptosis. It is responsible for the activation-induced apoptosis of peripheral T cells and functions as an effector molecule for cytotoxic T cells. FasL is expressed in activated lymphocytes, Sertoli cells, and some tumor cells.
Form
Liquid
Isotype
IgM
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Flow Cytometry
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Gene Info — Fasl
Entrez GeneID
14103Gene Name
Fasl
Gene Alias
APT1LG1, CD178, CD95L, Fas-L, Fas-Ligand, Faslg, Tnfsf6, gld
Gene Description
Fas ligand (TNF superfamily, member 6)
Gene Ontology
HyperlinkGene Summary
O
Other Designations
Fas antigen ligand|generalized lymphoproliferative disease|tumor necrosis factor (ligand) superfamily, member 6
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