ENDOG monoclonal antibody, clone 7G1G10
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Specifications
Product Description
Mouse monoclonal antibody raised against recombinant ENDOG.
Immunogen
Recombinant protein corresponding to amino acids 76-170 of human ENDOG.
Host
Mouse
Reactivity
Human, Rat
Form
Liquid
Isotype
IgG
Recommend Usage
Western Blot (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of ENDOG expression in HepG2 cell lysate with ENDOG monoclonal antibody, clone 7G1G10 (Cat # MAB2759) at (A) 5 and (B) 10 ug/mL . -
Gene Info — ENDOG
Entrez GeneID
2021Protein Accession#
n/aGene Name
ENDOG
Gene Alias
FLJ27463
Gene Description
endonuclease G
Omim ID
600440Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq
Other Designations
OTTHUMP00000022301
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Interactomes
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Pathways
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Publication Reference
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Apoptosis. DNA destroyers.
Hengartner MO.
Nature 2001 Jul; 412(6842):27.
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Mitochondrial endonuclease G is important for apoptosis in C. elegans.
Parrish J, Li L, Klotz K, Ledwich D, Wang X, Xue D.
Nature 2001 Jul; 412(6842):90.
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Endonuclease G is an apoptotic DNase when released from mitochondria.
Li LY, Luo X, Wang X.
Nature 2001 Jul; 412(6842):95.
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Apoptosis. DNA destroyers.
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