ABCC1 monoclonal antibody, clone IU2H10
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of MRP1 using ABCC1 monoclonal antibody, clone IU2H10 (Cat # MAB2388) on vector-transfected HEK293 cells (lane1), MRP1-transfected cells, prep1 (lane 2) and MRP1-transfected cells, prep2 (Lane 3). The lower band is a degradation product.
-
Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of ABCC1.
Immunogen
A synthetic peptide corresponding to amino acids 1-33 of human ABCC1.
Host
Mouse
Reactivity
Human, Mouse
Specificity
This antibody is specific to MRP1 protein.
Form
Liquid
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Transfected lysate)
Western blot analysis of MRP1 using ABCC1 monoclonal antibody, clone IU2H10 (Cat # MAB2388) on vector-transfected HEK293 cells (lane1), MRP1-transfected cells, prep1 (lane 2) and MRP1-transfected cells, prep2 (Lane 3). The lower band is a degradation product.Immunofluorescence
-
Gene Info — ABCC1
Entrez GeneID
4363Gene Name
ABCC1
Gene Alias
ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Omim ID
158343Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. [provided by RefSeq
Other Designations
ATP-binding cassette, sub-family C, member 1|LTC4 transporter|OTTHUMP00000045904|leukotriene C(4) transporter|multidrug resistance protein|multiple drug resistance protein 1|multiple drug resistance-associated protein
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com