Cell-Surface Vimentin (CSV) monoclonal antibody (Alexa 488)
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Specification
Product Description
Alexa 488 conjugated cell-surface vimentin (CSV) mouse monoclonal antibody.
Amenable Platform
Immunogen
Human recombinant vimentin
Host
Mouse
Form
Liquid
Conjugation
Alexa 488
Concentration
0.5 mg/mL
Isotype
IgG2b, kappa
Available Test
16 assays
Quality Control Testing
Results
Sandwich ELISA
Sandwich ELISA performed with CSV recombinant protein and CSV monoclonal antibody (Alexa 488)
Immunofluorescence
Immunofluorescence staining performed on PC-3 cells using Cell-Surface Vimentin (CSV) monoclonal antibody (Alexa 488) (10 ug/mL).
Recommend Usage
Immunofluorescence (10 ug/mL)
LiquidCell™ SuperSlide™ (6 uL per slide)Regulatory Status
Research Use Only
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at 2-8°C. Do not freeze.
Instrument Compatibility
Ventana™ BenchMark Stainer
Note
Cell-Surface Vimentin (CSV) antibody is a pending MD Anderson patent which has been exclusively licensed to Abnova Corporation.
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Applications
Immunofluorescence
Immunofluorescence staining performed on CTCs from the patient recoverd by SuperSlide™. CSV was detected via green signal (Alexa 488). -
Gene Info — VIM
Entrez GeneID
7431Gene Name
VIM
Gene Alias
FLJ36605
Gene Description
vimentin
Omim ID
193060Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract
Other Designations
OTTHUMP00000019224
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Interactome
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Disease
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