CITED4 monoclonal antibody, clone HT13-2D6.3
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More Files
- More Functions
Western Blot (Transfected lysate)
Detection of human CITED4 in 20ug of transfected whole cell Hep3B lysate using CITED4 monoclonal antibody, clone HT13-2D6.3 (Cat #MAB2352).
Photo courtesy of Dr. DeCaprio, DFCI.
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant CITED4.
Immunogen
Recombinant fusion protein corresponding to full length human CITED4.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Detection of human CITED4 in 20ug of transfected whole cell Hep3B lysate using CITED4 monoclonal antibody, clone HT13-2D6.3 (Cat #MAB2352).
Photo courtesy of Dr. DeCaprio, DFCI.Immunofluorescence
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CITED4
Entrez GeneID
163732Protein Accession#
Q96RK1Gene Name
CITED4
Gene Alias
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Gene Description
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
Omim ID
606815Gene Ontology
HyperlinkGene Summary
CITED4 belongs to a family of transcriptional coactivators that bind several proteins, including CREB-binding protein (MIM 600140) and p300 (MIM 602700).[supplied by OMIM
Other Designations
OTTHUMP00000009206|transcriptional co-activator 4
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Disease
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Publication Reference
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CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha.
Fox SB, Braganca J, Turley H, Campo L, Han C, Gatter KC, Bhattacharya S, Harris AL.
Cancer Research 2004 Sep; 64(17):6075.
Application：IHC-P, WB, Human, Human breast cancer, ECV304, MDA-MB-231 cells.
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CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha.
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