PMP22 monoclonal antibody, clone Hu1
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of PMP22 on formalin fixed, paraffin embedded dorsal root ganglion and spinal roots in 20 week fetal spinal cord preparation from rhesus monkey with PMP22 monoclonal antibody, clone Hu1 (Cat # MAB2301).
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of PMP22.
Immunogen
A synthetic peptide corresponding to amino acids 120-133 at the extracellular domain of human PMP22.
Host
Mouse
Reactivity
Human, Primates
Form
Liquid
Isotype
IgG1, kappa
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of PMP22 on formalin fixed, paraffin embedded dorsal root ganglion and spinal roots in 20 week fetal spinal cord preparation from rhesus monkey with PMP22 monoclonal antibody, clone Hu1 (Cat # MAB2301). -
Gene Info — PMP22
Entrez GeneID
5376Protein Accession#
Q01453Gene Name
PMP22
Gene Alias
CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, MGC20769, Sp110
Gene Description
peripheral myelin protein 22
Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein. [provided by RefSeq
Other Designations
growth arrest-specific 3
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Interactome
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Disease
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Publication Reference
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Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system.
Gregson NA, Zhang G, Pritchard J, Wang A, Sanvito L, Hayday AC, Hughes RA.
Journal of the Peripheral Nervous System : JPNS 2007 Mar; 12(1):2.
Application：IF, IHC-P, WB, Human, Mouse, Cauda equinae from patients without known neurological disease, HEK 293T cells, Human, mouse nerve sections, Fetal spinal cord, roots.
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Characterization of a monoclonal antibody specific for human peripheral myelin protein 22 and its use in immunohistochemical studies of the fetal and adult nervous system.
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