POR monoclonal antibody, clone AEFH-16
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human POR.
Immunogen
A synthetic peptide corresponding to human POR.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human, mouse, rat POR, in native form and recombinant. Superfamily members of POR are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:1000-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of A-431 cell lysate. -
Gene Info — POR
Entrez GeneID
5447Protein Accession#
P16435Gene Name
POR
Gene Alias
CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
Gene Description
P450 (cytochrome) oxidoreductase
Gene Ontology
HyperlinkGene Summary
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq
Other Designations
NADPH-dependent cytochrome P450 reductase|cytochrome P450 reductase
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Interactome
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