TRIP11 monoclonal antibody, clone 10G5
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant TRIP11.
Immunogen
Recombinant GST fusion protein corresponding to amino acids 1099-1372 of TRIP11.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes human Trip230, a 230 kD protein. Trip230 interacts with Retinoblasoma Protein (Rb) and thyroid hormone receptor using two distinct domains.
Form
Liquid
Isotype
IgG1, kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1-5 ug/mL)
Immunoprecipitation (1-5 ug/mL)
Immunofluorescence (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunoprecipitation
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Gene Info — TRIP11
Entrez GeneID
9321Gene Name
TRIP11
Gene Alias
CEV14, GMAP-210, TRIP230
Gene Description
thyroid hormone receptor interactor 11
Omim ID
604505Gene Ontology
HyperlinkGene Summary
TRIP11 was first identified through its ability to interact functionally with thyroid hormone receptor-beta (THRB; MIM 190160). It has also been found in association with the Golgi apparatus and microtubules.[supplied by OMIM
Other Designations
thyroid receptor interacting protein 11
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Interactome
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Disease
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Publication Reference
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Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus.
Chen Y, Chen PL, Chen CF, Sharp ZD, Lee WH.
PNAS 1999 Apr; 96(8):4443.
Application：IF, IP, WB-Ce, WB-Tr, Human, Monkey, CV1, T24 cells.
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A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein.
Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH.
PNAS 1997 Aug; 94(17):9040.
Application：IP, Human, T24 cells.
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Thyroid hormone, T3-dependent phosphorylation and translocation of Trip230 from the Golgi complex to the nucleus.
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