EDA2R monoclonal antibody, clone 4A6B4

Catalog # MAB21461

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Price

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Quantity

Size:100 ug
Price: USD $ 531.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of Lane 1: HEK293 and Lane 2: EDA2R-hIgGFc transfected HEK293 cell lysates with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).

Enzyme-linked Immunoabsorbent Assay
Application

Enzyme-linked Immunoabsorbent Assay

ELISA analysis with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).

Flow Cytometry
Application

Flow Cytometry

Flow cytometric analysis of MOLT4 cells with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461) (Green). Red: Negative Control.

  • Specification

    Product Description

    Mouse monoclonal antibody raised against partial recombinant human EDA2R.

    Immunogen

    Recombinant protein corresponding to amino acids 1-138 of human EDA2R.

    Host

    Mouse

    Theoretical MW (kDa)

    32.8

    Reactivity

    Human

    Form

    Liquid

    Isotype

    IgG2b

    Recommend Usage

    ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS (0.05% sodium azide).

    Storage Instruction

    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot analysis of Lane 1: HEK293 and Lane 2: EDA2R-hIgGFc transfected HEK293 cell lysates with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).

    Enzyme-linked Immunoabsorbent Assay

    ELISA analysis with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461).

    Flow Cytometry

    Flow cytometric analysis of MOLT4 cells with EDA2R monoclonal antibody, clone 4A6B4 (Cat # MAB21461) (Green). Red: Negative Control.
  • Gene Info — EDA2R

    Entrez GeneID

    60401

    Protein Accession#

    Q9HAV5

    Gene Name

    EDA2R

    Gene Alias

    EDA-A2R, EDAA2R, TNFRSF27, XEDAR

    Gene Description

    ectodysplasin A2 receptor

    Omim ID

    300276

    Gene Ontology

    Hyperlink

    Gene Summary

    EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support. [provided by RefSeq

    Other Designations

    EDA-A2 receptor|OTTHUMP00000023448|X-linked ectodysplasin receptor|X-linked ectodysplasin-A2 receptor|tumor necrosis factor receptor superfamily member XEDAR

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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