TPH1 monoclonal antibody, clone EDH-20
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human TPH1.
Immunogen
A synthetic peptide corresponding to human TPH1.
Host
Rabbit
Theoretical MW (kDa)
50.985
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — TPH1
Entrez GeneID
7166Protein Accession#
P17752Gene Name
TPH1
Gene Alias
MGC119994, TPH, TPRH
Gene Description
tryptophan hydroxylase 1
Omim ID
191060Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others
Other Designations
indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase|tryptophan 5-monooxygenase|tryptophan hydroxylase (tryptophan 5-monooxygenase)
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Interactome
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Pathway
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Disease
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