ADAMTS1 monoclonal antibody, clone 1C12E6
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human ADAMTS1.
Immunogen
Recombinant protein corresponding to amino acids 858-960 of human ADAMTS1 from E. coli.
Host
Mouse
Theoretical MW (kDa)
24.7
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200 - 1:400)
Immunocytochemistry
Immunohistochemistry
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell with ADAMTS1 monoclonal antibody.Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) ADAMTS1-hIgGFc transfected HEK293 cell lysate with ADAMTS1 monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of ADAMTS1 monoclonal antibody, clone 1C12E6.Flow Cytometry
Flow cytometric analysis of HeLa cells with ADAMTS1 monoclonal antibody (green) and negative control (red). -
Gene Info — ADAMTS1
Entrez GeneID
9510Gene Name
ADAMTS1
Gene Alias
C3-C5, KIAA1346, METH1
Gene Description
ADAM metallopeptidase with thrombospondin type 1 motif, 1
Omim ID
605174Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function. [provided by RefSeq
Other Designations
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1|human metalloproteinase with thrombospondin type 1 motifs
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Interactome
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Disease
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