CHRNA4 monoclonal antibody, clone 7B4H1
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human CHRNA4.
Immunogen
Recombinant protein corresponding to amino acid 29-242 of human CHRNA4 from E. coli.
Host
Mouse
Theoretical MW (kDa)
70
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) CHRNA4-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CHRNA4 monoclonal antibody, clone 7B4H1. -
Gene Info — CHRNA4
Entrez GeneID
1137Gene Name
CHRNA4
Gene Alias
BFNC, EBN, EBN1, FLJ95812, NACHR, NACHRA4, NACRA4
Gene Description
cholinergic receptor, nicotinic, alpha 4
Gene Ontology
HyperlinkGene Summary
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. [provided by RefSeq
Other Designations
cholinergic receptor, nicotinic, alpha 4 subunit|cholinergic receptor, nicotinic, alpha polypeptide 4|neuronal nicotinic acetylcholine receptor alpha-4 subunit
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Interactome
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