HIST2H3C(27Ac) monoclonal antibody, clone 2D7B3
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human HIST2H3C(27Ac).
Immunogen
A synthetic peptide corresponding to amino acid of human HIST2H3C(27Ac).
Host
Mouse
Theoretical MW (kDa)
15.4kDa
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot
Immunohistochemistry (1:200-1:1000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded breast cancer tissues with HIST2H3C(27Ac) monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of HIST2H3C(27Ac) monoclonal antibody, clone 2D7B3.Flow Cytometry
Flow cytometric analysis of HeLa cells with HIST2H3C(27Ac) monoclonal antibody (green) and negative control (red). -
Gene Info — HIST2H3C
Entrez GeneID
126961Gene Name
HIST2H3C
Gene Alias
H3, H3.2, H3/M, H3F2, H3FM, MGC9629
Gene Description
histone cluster 2, H3c
Omim ID
142780Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq
Other Designations
H3 histone family, member M|H3 histone, family 2|OTTHUMP00000014041|histone 2, H3c
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