HDAC4 monoclonal antibody, clone 5E4A5
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of (1) HEK293 cells, (2) HDAC4-hIgGFc transfected HEK293 cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded endometrial cancer tissues with HDAC4 monoclonal antibody.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of HDAC4 monoclonal antibody, clone 5E4A5.
Flow Cytometry
Flow cytometric analysis of HeLa cells with HDAC4 monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human HDAC4.
Immunogen
Recombinant protein corresponding to amino acid 456-592 of human HDAC4 from E. coli.
Host
Mouse
Theoretical MW (kDa)
119kDa
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of (1) HEK293 cells, (2) HDAC4-hIgGFc transfected HEK293 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded endometrial cancer tissues with HDAC4 monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of HDAC4 monoclonal antibody, clone 5E4A5.Flow Cytometry
Flow cytometric analysis of HeLa cells with HDAC4 monoclonal antibody (green) and negative control (red). -
Gene Info — HDAC4
Entrez GeneID
9759Gene Name
HDAC4
Gene Alias
HA6116, HD4, HDAC-A, HDACA, KIAA0288
Gene Description
histone deacetylase 4
Omim ID
605314Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq
Other Designations
histone deacetylase A
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Interactome
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Disease
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