BST1 monoclonal antibody, clone SY11B5
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Specification
Product Description
Mouse monoclonal antibody raised against human BST1.
Immunogen
Human BST1.
Host
Mouse
Reactivity
Human, Non-Human Primates
Specificity
This antibody recognizes CD157, an approximately 45 kDa GPI-anchored protein expressed mainly on monocytes, macrophages, granulocytes and bone marrow stromal cells.
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Flow Cytometry
Immunoprecipitation
Immunohistochemistry (Frozen sections)
Western Blot (non-reducing conditions)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (15 mM sodium azide).
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis (surface staining) of human peripheral blood leukocytes with anti-human BST1 APC. -
Gene Info — BST1
Entrez GeneID
683Gene Name
BST1
Gene Alias
CD157
Gene Description
bone marrow stromal cell antigen 1
Omim ID
600387Gene Ontology
HyperlinkGene Summary
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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