SSX2 monoclonal antibody, clone CL3202
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with SSX2 monoclonal antibody, clone CL3202 (Cat # MAB15795) shows strong nuclear immunoreactivity in a subset of cells in seminiferous tubules.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human SSX2.
Immunogen
Recombinant protein corresponding to human SSX2.
Epitope
This antibody binds to an epitope located within the peptide sequence GKHAWTHRLRERKQL as determined by overlapping synthetic peptides.
Sequence
GKHAWTHRLRERKQLVIYEEISDPEEDDE
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with SSX2 monoclonal antibody, clone CL3202 (Cat # MAB15795) shows strong nuclear immunoreactivity in a subset of cells in seminiferous tubules. -
Gene Info — SSX2
Entrez GeneID
6757Protein Accession#
Q16385Gene Name
SSX2
Gene Alias
HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX
Gene Description
synovial sarcoma, X breakpoint 2
Omim ID
300192Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000024290|OTTHUMP00000024291|sarcoma, synovial, X-chromosome-related 2|synovial sarcoma, X breakpoint 2, isoform b|synovial sarcoma, X breakpoint 2B
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