CGB monoclonal antibody, clone PC-2
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Specification
Product Description
Mouse monoclonal antibody raised against native CGB.
Immunogen
Native purified human CGB.
Host
Mouse
Reactivity
Human
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 1.2% sodium acetate (2 mg BSA, 0.01 mg sodium azide)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 1 mL of 1.2% sodium acetate or neutral PBS and concentration will be 100 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — CGB
Entrez GeneID
1082Gene Name
CGB
Gene Alias
CGB3, hCGB
Gene Description
chorionic gonadotropin, beta polypeptide
Omim ID
118860Gene Ontology
HyperlinkGene Summary
This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq
Other Designations
chorionic gonadotropin beta 3 subunit|chorionic gonadotropin beta chain|chorionic gonadotropin beta subunit
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Interactome
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Disease
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Publication Reference
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Characterization of human chorionic gonadotropin as a novel angiogenic factor.
Zygmunt M, Herr F, Keller-Schoenwetter S, Kunzi-Rapp K, Munstedt K, Rao CV, Lang U, Preissner KT.
The Journal of Clinical Endocrinology and Metabolism 2002 Nov; 87(11):5290.
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Identification of the transcriptionally active genes of the chorionic gonadotropin beta gene cluster in vivo.
Bo M, Boime I.
The Journal of Biological Chemistry 1992 Feb; 267(5):3179.
Application:WB-Ce, WB-Ti, WB-Tr, Human, Mammalian cells, Tissues.
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The beta subunit of human chorionic gonadotropin is encoded by multiple genes.
Policastro P, Ovitt CE, Hoshina M, Fukuoka H, Boothby MR, Boime I.
The Journal of Biological Chemistry 1983 Oct; 258(19):11492.
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Characterization of human chorionic gonadotropin as a novel angiogenic factor.
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