MUSK monoclonal antibody, clone 10A4
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using MUSK monoclonal antibody, clone 10A4 (Cat # MAB10428) with DAB staining.
Immunofluorescence
Confocal immunofluorescence analysis of 293 cells using MUSK monoclonal antibody, clone 10A4 (Cat # MAB10428) (green). Blue: DRAQ5 fluorescent DNA dye.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant MUSK.
Immunogen
Recombinant protein corresponding to human MUSK.
Host
Mouse
Theoretical MW (kDa)
97
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascitic (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using MUSK monoclonal antibody, clone 10A4 (Cat # MAB10428) with DAB staining.Immunofluorescence
Confocal immunofluorescence analysis of 293 cells using MUSK monoclonal antibody, clone 10A4 (Cat # MAB10428) (green). Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MUSK
Entrez GeneID
4593Gene Name
MUSK
Gene Alias
MGC126323, MGC126324
Gene Description
muscle, skeletal, receptor tyrosine kinase
Gene Ontology
HyperlinkGene Summary
Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM
Other Designations
protein-tyrosine kinase|receptor tyrosine kinase|skeletal muscle receptor tyrosine kinase
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Interactome
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Disease
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