FemtoDetect™ IL1B (Human) ELISA Kit
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Specification
Product Description
FemtoDetect™ IL1B (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of Human IL-1 beta (Interleukin 1 beta) in serum, plasma and other biological fluids.
Suitable Sample
serum, plasma and other biological fluids
Sample Volume
100 uL
Detection Method
Colormetric
Assay Type
Quantitative
Calibration Range
0.63-40 pg/mL
Limit of Detection
0.39 pg/mL
Specificity
This kit recognizes Human IL-1 beta in samples.No significant cross-reactivity or interference between Human IL-1 beta and analogues was observed
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 2-8°C. For long term storage store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Quantification
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Gene Info — IL1B
Entrez GeneID
3553Gene Name
IL1B
Gene Alias
IL-1, IL1-BETA, IL1F2
Gene Description
interleukin 1, beta
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
Other Designations
catabolin|preinterleukin 1 beta|pro-interleukin-1-beta
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Pathway
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Disease
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