FastELISA™ CST3 (Human) ELISA Kit
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Specification
Product Description
FastELISA™ CST3 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of Human CST3 (Cystatin C) in Serum, plasma.
Suitable Sample
Serum, Plasma, etc.
Sample Volume
50 uL
Detection Method
Colormetric
Assay Type
Quantitative
Calibration Range
78.1-5000 pg/mL
Limit of Detection
25 pg/mL
Specificity
This assay is highly specific for detection of Human CST3. No significant cross-reactivity or interference between Human CST3 and analogues was observed.
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 2-8°C for 6 months. For long term storage store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Quantification
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Gene Info — CST3
Entrez GeneID
1471Gene Name
CST3
Gene Alias
ARMD11, MGC117328
Gene Description
cystatin C
Gene Ontology
HyperlinkGene Summary
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq
Other Designations
OTTHUMP00000030440|OTTHUMP00000164181|OTTHUMP00000164182|bA218C14.4 (cystatin C)|cystatin 3|cystatin C (amyloid angiopathy and cerebral hemorrhage)|gamma-trace|neuroendocrine basic polypeptide|post-gamma-globulin
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Interactome
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Disease
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