AKR1C3 (Human) ELISA Kit
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Specification
Product Description
AKR1C3 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for quantitative detection of human AKR1C3 in cell culture supernates, serum and plasma (heparin, EDTA).
Suitable Sample
Cell culture supernates, serum and plasma (heparin, EDTA)
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
156 to 10000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Quality Control Testing
Standard curve
The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for six months. For long term storage store at -20°C.
Avoid repeated freezing and thawing. -
Applications
Quantification
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Gene Info — AKR1C3
Entrez GeneID
8644Protein Accession#
P42330Gene Name
AKR1C3
Gene Alias
DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS
Gene Description
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
Omim ID
603966Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
Other Designations
OTTHUMP00000018996|aldo-keto reductase family 1, member C3|chlordecone reductase|dihydrodiol dehydrogenase 3|dihydrodiol dehydrogenase X|hydroxysteroid (17-beta) dehydrogenase 5|prostaglandin F synthase|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase|type
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