COL1A1 (Human) ELISA Kit
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Specification
Product Description
COL1A1 (Human) ELISA Kit is a sandwich enzyme-linked immunosorbent assay for the quantitative measurement of human COL1A1 in cell culture supernatants, serum and plasma (heprain, EDTA, citrate).
Suitable Sample
Cell Culture Supernatants, Plasma (Heprain, EDTA, Citrate) and Serum.
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
31.2 to 2000 pg/mL
Reactivity
Human
Regulatory Status
For research use only (RUO)
Storage Instruction
Store at 4°C for short term. Store at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — COL1A1
Entrez GeneID
1277Gene Name
COL1A1
Gene Alias
OI4
Gene Description
collagen, type I, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
Other Designations
alpha 1 type I collagen|collagen alpha 1 chain type I|collagen of skin, tendon and bone, alpha-1 chain|pro-alpha-1 collagen type 1|type I collagen alpha 1 chain
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