HDAC8 Deacetylase Fluorometric (Human) Assay Kit
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More Files
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Dose dependent curve of recombinant HDAC8.
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Specification
Product Description
HDAC8 Deacetylase Fluorometric (Human) Assay Kit is designed for the rapid and sensitive evaluation of HDAC inhibitors using recombinant HDAC8. Additionally, any cultured primary cell, cell line, or tissue homogenate can be assayed for HDAC8 activity with the HDAC8 deacetylase fluorometric assay kit after immunoprecipitation with an appropriate HDAC8 specific antibody.
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Dose dependent curve
Dose dependent curve of recombinant HDAC8.
Storage Instruction
Store the kit at -80°C. Do not expose reagents to excessive light.
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Applications
Functional Study
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Gene Info — HDAC8
Entrez GeneID
55869Gene Name
HDAC8
Gene Alias
HDACL1, RPD3
Gene Description
histone deacetylase 8
Omim ID
300269Gene Ontology
HyperlinkGene Summary
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. [provided by RefSeq
Other Designations
histone deacetylase-like 1
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Interactome
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Disease
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