GAD1 (Human) Cell-Based ELISA Kit
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Specification
Product Description
GAD1 (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of GAD1 expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — GAD1
Entrez GeneID
2571Protein Accession#
Q99259Gene Name
GAD1
Gene Alias
FLJ45882, GAD, SCP
Gene Description
glutamate decarboxylase 1 (brain, 67kDa)
Gene Ontology
HyperlinkGene Summary
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. [provided by RefSeq
Other Designations
OTTHUMP00000041055|glutamate decarboxylase 1|glutamate decarboxylase 1 (brain, 67kD)
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