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Qualitative

Entrez GeneID

Protein Accession#

Gene Name

TFAP2A

Gene Alias

AP-2, AP-2alpha, AP2TF, BOFS, TFAP2

Gene Description

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Omim ID

Gene Ontology

Gene Summary

AP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM

Other Designations

OTTHUMP00000016013|OTTHUMP00000016014|activating enhancer-binding protein 2 alpha|transcription factor AP-2 alpha|transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)

Entrez GeneID

Protein Accession#

Gene Name

TFAP2B

Gene Alias

AP-2B, AP2-B, MGC21381

Gene Description

transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. [provided by RefSeq

Other Designations

OTTHUMP00000039925|activating enhancer binding protein 2 beta|transcription factor AP-2 beta